The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

The severity of factor X deficiency varies from person to person. Your body still produces 40% or more of the normal amount of factor X in mild cases. You may have no symptoms or only very minor ones.

‌Factor VII deficiency is a rare genetic disorder. It occurs when your body can’t produce enough clotting factor VII, which helps in healing wounds. It can be hereditary or be caused by an underlying ...

Coagulation factors, which are involved in blood clotting after injury, may offer new strategies for fighting multidrug-resistant bacteria, according to a new study. Coagulation factors, which are ...

Hemophilia A, also known as classic hemophilia or factor VIII deficiency, is a bleeding disorder. It occurs when certain proteins are missing in the blood, causing people to bleed and bruise easily.

Researchers used a technique in genetic analysis termed Mendelian randomization to examine 12 coagulation measures, uncovering four that are associated with migraine susceptibility. Nearly 15 percent ...

In clinical laboratory settings, coagulation factor tests are routinely conducted to identify inherited or acquired deficiencies in patients suspected of an ongoing bleeding risk. These tests ...

A person’s blood clot risk factors can include some acquired or genetic conditions. Although blood clotting plays an important role in protecting a person’s body, abnormal blood clots can be fatal.

A unique subset of white blood cells confers fast-acting and lasting protection against ischemic stroke in mice, University of Pittsburgh neurologists and immunologists reported in the Journal of ...

For more than 40 years as a researcher and clinician, Joseph Broderick has actively contributed to improvements in stroke care, occupying a front row seat to seismic innovations: the clinical trials ...