A 32-bp deletion in this gene (CCR5-Δ32 mutation) results in a nonfunctioning receptor that is trapped in the endoplasmic reticulum and therefore not expressed at the cell surface. 19, 20 The mutation ...

Immune cells expressing the receptor CCR5 are recruited to areas of inflammation by chemokine ligands, making CCR5 an attractive therapeutic target for preventing cell trafficking during conditions ...

Human immunodeficiency virus (HIV) infection is a viral infection that causes acquired immunodeficiency syndrome (AIDS) by gradually destroying certain leukocytes. When HIV enters the human body, it ...

When He Jiankui announced the birth of twin girls whose DNA he had modified when they were embryos using the CRISPR gene-editing tool, he justified his actions on the ground that he had given the two ...

RICHMOND, Calif., Feb. 3 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced today that its collaborators at the University of Pennsylvania ...

In a recent study published in the Clinical Infectious Diseases journal, researchers assessed the impact of long coronavirus disease 2019 (COVID-19) on C-C chemokine receptor-5 (CCR5) and ...

In the three and a half decades since HIV/AIDS was discovered, the deadly disease has killed 35 million people. While drugs now allow patients to live long lives with the virus, only one man, an ...

With Gift Aid, your generous donation of £10 would be worth £12.50 at no extra cost to you. Yes, I want to Gift Aid any donations made to NAM now, in the future and in the past four years I am a UK ...

I am a millennial, which means that along with my deft technology skills and love for social media, I am also a member of the first generation to have never lived in an HIV-free world since the ...

The first people to be gene-edited - a pair of baby twin girls - may have been mutated in a way that shortens life expectancy, research suggests. Prof He Jiankui shocked the world when he genetically ...