A new study maps the immune cell landscape of bone marrow in patients with multiple myeloma, a rare cancer that develops in ...
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Single-cell analysis illuminates myeloma immune landscape
Scientists at the Icahn School of Medicine at Mount Sinai, in partnership with the Multiple Myeloma Research Foundation (MMRF ...
The map was developed by using single-cell RNA sequencing to analyze 1.4 million plasma and immune cells in bone marrow from over 300 patients.
Inflammation covertly rewires the bone marrow, enabling mutated stem cells to rise and setting the stage for future blood disease.
Multiple myeloma, a cancer of the bone marrow, remains difficult to treat despite modern CAR T cell therapies. In recent research, a team led by Dr. Armin Rehm presents an improved immunotherapy that ...
Stem cells form the backbone of many cell-based therapies due to their unique properties, including the ability to self-renew and differentiate to many cell types. Multiple cell therapies deliver ...
Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...
A bone marrow transplant process co-developed by investigators at the Johns Hopkins Kimmel Cancer Center is safe and curative for adults with sickle cell disease, according to results of a trial ...
A bone marrow transplant, or stem cell transplant, places blood stem cells back into the body. The transplant replaces cells that cancer or treatments have destroyed. People may have a bone marrow ...
Researchers at WashU Medicine and their collaborators have created an immune cell atlas of multiple myeloma, a cancer of the ...
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